Genomics England
GMS Panels
Panels
Genes and Entities

TREM2

triggering receptor expressed on myeloid cells 2
OMIM: 605086
PanelMode of inheritanceDetails
4 panels
Green
in Adult onset leukodystrophy
R-numbers: R62
Signed-off version 5.0
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2, 618193
Green
in Adult onset neurodegenerative disorder
R-numbers: R58
Signed-off version 6.6
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2, OMIM:618193, Dystonia
Green
in Skeletal dysplasia
Component of the following Super Panels:
  • - Paediatric disorders
R-numbers: R104
Signed-off version 6.16
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Nasu-Hakola disease 221770
Green
in White matter disorders and cerebral calcification - narrow panel
Component of the following Super Panels:
  • - Childhood onset leukodystrophy
Signed-off version 5.3
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
POLYCYSTIC LIPOMEMBRANOUS OSTEODYSPLASIA WITH SCLEROSING LEUKOENCEPHALOPATHY, Calcifications in basal ganglia, Nasu-Hakola disease, Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL)