Genomics England
GMS Panels
Panels
Genes and Entities

MYBPC3

myosin binding protein C, cardiac
OMIM: 600958
PanelMode of inheritanceDetails
3 panels
Green
in Dilated and arrhythmogenic cardiomyopathy
Component of the following Super Panels:
  • - Sudden unexplained death or survivors of a cardiac event
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R132
Signed-off version 2.32
MONOALLELIC, autosomal or pseudoautosomal, NOT imprinted
Phenotypes
Cardiomyopathy, dilated, 1MM, Cardiomyopathy, hypertrophic, 4 (115197), Left ventricular noncompaction 10 (615396), Cardiomyopathy, dilated, 1MM (615396)
Green
in Hypertrophic cardiomyopathy
Component of the following Super Panels:
  • - Sudden unexplained death or survivors of a cardiac event
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R131
Signed-off version 4.16
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
Cardiomyopathy, familial hypertrophic, 4,, Cardiomyopathy, hypertrophic, 4 (115197), Left ventricular noncompaction 10 (615396), Cardiomyopathy, dilated, 1MM (615396)
Green
in Paediatric or syndromic cardiomyopathy
Component of the following Super Panels:
  • - Unexplained death in infancy and sudden unexplained death in childhood
R-numbers: R135
Signed-off version 5.13
BOTH monoallelic and biallelic, autosomal or pseudoautosomal
Phenotypes
Cardiomyopathy, familial hypertrophic, 4,, Cardiomyopathy, dilated, 1MM, Hypertrophic cardiomyopathy, Left ventricular noncompaction 10,