Genomics England
GMS Panels
Panels
Genes and Entities

LCK

LCK proto-oncogene, Src family tyrosine kinase
OMIM: 153390
PanelMode of inheritanceDetails
1 panel
Green
in Primary immunodeficiency or monogenic inflammatory bowel disease
R-numbers: R15
Signed-off version 6.12
BIALLELIC, autosomal or pseudoautosomal
Phenotypes
Immunodeficiency 22, 615758, LCK deficiency, Combined immunodeficiency, Severe combined immunodeficiency due to LCK deficiency, Recurrent infections, immune dysregulation, autoimmunity, Immunodeficiencies affecting cellular and humoral immunity